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Showing posts from March, 2020

Utilizing Single Cells To Get the Whole Picture of the Epigenetic

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Genes may control what qualities are passed down from parent to posterity, but every cell expresses these genes distinctively dependent on “external” epigenetic modifications.   Epigenetics doesn't adjust the quality arrangement (genotype), however, they do impact cell behavior and function (phenotype). The study of epigenetics helps us see how phenotypic changes lead to malady, stem cell differentiation, and essentially, what drives the fate of every cell in the human body. The epigenome isn't reliable between cells, or even between cells of a similar sort. Individual changes travel every which way all through a cell's lifetime. In this way, researchers are confronted with the precarious test as they attempt to the role of epigenetics in infection and development. Understanding intercellular heterogeneity is key here. The epigenome must be inspected at single-cell resolution. Now with the advancement of single-cell sequencing strategies like the single

Nanotechnology Platform Could Improve Stem Cell Transplantation?

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Stem cells can grow into many non-identical kinds of cells, including neurons that transmit information within the brain. Adult human-induced pluripotent stem cells, which resemble embryonic stem cells , are often used to develop drugs and model diseases. While stem cells hold great potential for treating neurodegenerative diseases and central nervous system injuries, controlling and characterizing their fate are critical issues that need to be addressed before their potential use as treatments is often fully realized. Current methods for characterizing stem cell biomarkers destroy cellular activities and functions, which makes it difficult to conduct more definitive research that might cause biomedical applications. Using their nanotechnology platform, the scientists successfully monitored the generation of neurons from human stem cells by characterizing next-generation biomarkers called exosomes—tiny particles released by cells that play a critical role in cell-to-cel

Could Stem Cells Help Corona virus Disease COVID-19 Patients?

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Patients who were dealt with while in a serious condition have been released after recuperation. Stem cells can self-renew or multiply while maintaining the potential to become other sorts of cells. They can become cells of the blood, heart, lungs or other body parts.  Stem cells even have a strong function, advancing the formation of the newest blood vessels, cell proliferation, and differentiation and inhibiting inflammatory response, experts say. Stem cell therapy has been utilized in the treatment of some infectious diseases and complications. For instance, it's been tried in treating H7N9 avian flu and showed good results. Human and animal studies have shown that after infection with coronavirus, the rapid replication of the virus in the body and the subsequent inflammatory response cause damage to alveolar epithelial cells and capillary endothelial cells, causing diffuse interstitial and alveolar edema, and pulmonary function. Impaired, leading to acute hy